Vitiligo is a condition that causes the skin to lose its color or pigmentation. It develops when the immune system starts attacking melanocytes, which are cells that produce the skin pigment melanin. The affected areas of the skin turn lighter or even white. These changes in skin color are typically observed around the hands, feet, arms, and face. Today, there are several ways to manage vitiligo, one of the most common options being Opzelura (ruxolitinib).

Opzelura for vitiligo treatment
A prescription-based option, Opzelura (ruxolitinib), helps treat the most common form of the condition called nonsegmental vitiligo. Here , depigmentation can be observed on both sides of the body. Opzelura can help tackle this loss of pigment; it is a topical prescription, so it is supposed to be applied to the skin. This is an FDA-approved treatment for adults and children at least 12 years old.

Benefits

• Opzelura can help restore some of the lost pigment over time. It is known to restore pigment on the face and body, covering up to 10% of the surface area.
• This treatment option is considered to be a safe way to target depigmentation.
• Since it is a topical option, one can apply the cream independently i.e., without assistance.
• The cream can be used directly on multiple areas, including sensitive spots around the mouth and eyes. 

That said, one should consult a healthcare professional before using Opzelura.

Usage guidelines
While one can use Opzelura at home, they must follow doctor-recommended application instructions.

• A doctor may recommend using the topical cream twice daily on depigmented areas of skin, covering up to 10% of the body’s surface area.
• The cream can be used once in the morning and once in the evening.
• One must apply a thin layer of the topical cream.
• One should wash their hands after applying Opzelura unless cream has been used on them.
• One must also discuss the Opzelura application with a doctor if one has other commitments, such as personal hygiene routines or the use of cosmetic products.

Results
Following a series of clinical studies, experts determined the benefits of pigment restoration over six months, one year, and two years.

• At six months, about one-third of participants who applied the topical solution saw a 75% improvement in vitiligo-affected facial areas.
• After a year, about half of the participants saw an improvement of nearly 75% in affected areas on the face.
• At two years, two-thirds of those who had not yet reached near complete repigmentation saw a 75% improvement in a score that measured vitiligo-affected areas on the face.

Payment options
Eligible patients can get an Opzelura copay savings card. Through the Opzelura Copay Savings Program, one might be able to pay as little as $0 for each tube. One can download the card directly or get it over mail or text. Additionally, eligible patients with commercial insurance may have to pay as little as $0 per Opzelura tube.